WB
Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.FC
Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).| Product Name | Mouse Monoclonal Antibody to CD126 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Purified recombinant fragment of human CD126 (AA:EXTRA 20-177) expressed in E. Coli. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FCWB |
| WB:1:500-1:2000 IHC:1:200-1:400 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IL6R |
|---|---|
| Gene Synonyms | IL6Q gp80 CD126 HIES5 IL-6R IL6RA IL6RQ IL-1Ra IL-6RA IL6QTL IL-6R-1 |
| Gene Full Name | interleukin 6 receptor |
| Gene Summary | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020] |
| Alternative Names | IL6Q gp80 CD126 HIES5 IL-6R IL6RA IL6RQ IL-1Ra IL-6RA IL6QTL IL-6R-1 |
| Molecular Weight(MW) | 52kDa |
| Cellular Localization | Cell membrane,Membrane,Secreted. |
WB
Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.
FC
Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).| Application Notes | WB:1:500-1:2000 IHC:1:200-1:400 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
