IHC
Predicted cell location: Cytoplasm . Positive control: Human cervical cancer . Recommended dilution: 30-150. The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Anti-GSKIP rabbit polyclonal antibody at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)| Product Name | Anti-GSKIP rabbit polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Fusion protein of human GSKIP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:30 ~ 1:150 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GSKIP |
|---|---|
| Gene Synonyms | HSPC210 C14orf129 |
| Gene Full Name | GSK3B interacting protein |
| Gene Summary | This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] |
| Alternative Names | GSK3B interacting protein HSPC210 C14orf129 |
| Cellular Localization | Cytoplasm,Nucleus. |
IHC
Predicted cell location: Cytoplasm . Positive control: Human cervical cancer . Recommended dilution: 30-150. The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Anti-GSKIP rabbit polyclonal antibody at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)| Application Notes | IHC:1:30 ~ 1:150 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -20°C. |
| Storage Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
