The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Molecular Weight(MW)
37 KDa
Cellular Localization
Golgi apparatus,Membrane,Secreted.
Application
WB
Western blot analysis of ST3GAL1 expression in HEK293T (A) whole
cell lysates.
IHC
Immunohistochemical analysis of ST3GAL1 staining in human tonsil
formalin fixed paraffin embedded tissue section.
Application Notes
WB:1:500-1:1000 IHC:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Storage Buffer
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.