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LRRC8A/SWELL1 Polyclonal antibody

Catalog Number:OM646565
OM646565
Discount Price
OM646565-100ul
2~3 Week
100ul
2~3 Week
Product Profile
Product Name LRRC8A/SWELL1 Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant human LRRC8A protein.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IPWB
WB:1:500-1:1000
IP:0.5-4.0 ug for 1.0-3.0 mg of total protein lysate.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol LRRC8A
Gene Synonyms AGM5
LRRC8
SWELL1
HsLRRC8A
Gene Full Name leucine rich repeat containing 8 VRAC subunit A
Gene Summary This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Alternative Names LRRC8A
HsLRRC8A
KIAA1437
Leucine-rich repeat-containing protein 8A
LRRC8
Molecular Weight(MW) 94 kDa
Cellular Localization Cell membrane,Lysosome,Membrane.
Application

WB

WB analysis using LRRC8A/SWELL1 Polyclonal antibody Mouse brain tissue were subjected to SDS PAGE followed by western blot with LRRC8A/SWELL1 antibody at dilution of 1:500 incubated at room temperature for 1.5 hours.

IP

IP experiment of mouse brain using LRRC8A/SWELL1 Polyclonal antibody IP result of anti-LRRC8A/SWELL1 with mouse brain tissue lysate 2100 ug.
Application Notes WB:1:500-1:1000
IP:0.5-4.0 ug for 1.0-3.0 mg of total protein lysate.
Additional Information
Form Liquid
Storage Instructions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
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