This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]
Alternative Names
ADAM metallopeptidase domain 8 MS2 CD156 CD156a
Molecular Weight(MW)
89 kDa
Cellular Localization
Membrane.
Application
WB
Gel: 6%SDS-PAGE,
Lysate: 30 μg,
Lane 1-2: K562, Mouse pancreas lysates,
Primary antibody: ADAM8 Antibody at dilution 1/1000,
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 3 minutes.