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Polyclonal Antibody to Stanniocalcin 1 (STC1)

Catalog Number:OM646656
OM646656
Discount Price
OM646656-100ul
100ul
Product Profile
Product Name Polyclonal Antibody to Stanniocalcin 1 (STC1)
Antibody Type Primary Antibodies
Immunogen Recombinant STC1 (Ser28~Ala247) expressed in E.coli
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:250-1:1000
IHC::1:25-1:100
Species Reactivity Human
Concentration 0.5mg/ml
Purification Protein A
Target Information
Gene Symbol STC1
Gene Synonyms STC
Gene Full Name stanniocalcin 1
Gene Summary This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 55 kDa
Application

WB

Figure. Western Blot; Sample: Recombinant STC1, Human.

IHC

DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 20µg/ml Rabbit Anti-Human STC1 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

IHC

DAB staining on IHC-P;Samples: Human Breast cancer Tissue.
Application Notes WB:1:250-1:1000
IHC::1:25-1:100
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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