WB
Western Blot. Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, K562 whole cell lysate. All lanes: Factor IX antibody at 1:2000. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.| Product Name | F9 Recombinant Monoclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human Factor IX. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | F9 |
|---|---|
| Gene Synonyms | FIX P19 PTC HEMB THPH8 F9 p22 |
| Gene Full Name | coagulation factor IX |
| Gene Summary | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015] |
| Alternative Names | Coagulation factor IX (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain Coagulation factor IXa heavy chain] F9 |
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Secreted. |
WB
Western Blot. Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, K562 whole cell lysate. All lanes: Factor IX antibody at 1:2000. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.| Application Notes | WB:1:500-1:5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
