WB
Western Blot. Positive WB detected in Recombinant protein. All lanes: E3L antibody at 1:2000. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.| Product Name | Rabbit anti-E3L Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Vaccinia virus Protein E3 (E3L) (1-190AA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:200-1:2000 |
|
| Species Reactivity | Fruit Fly |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | E3L |
|---|---|
| Alternative Names | Protein E3 (p25) |
| Molecular Weight(MW) | 28.5 kDa(Observed band size:29 kDa) |
| Function | Plays a role in the inhibition of multiple cellular antiviral responses activated by dsRNA, such as inhibition of PKR activation, apoptosis, and IFN-mediated antiviral activities. Blocks also the phosphorylation and subsequent activation of IRF3 and IRF7 kinases that are required for interferon-alpha gene expression. Inhibits NF-kappa-B activation and the ubiquitin-like protein ISG15, which is an early antiviral protein. The binding with host ISG15 subsequently blocks host ISGylation. Inhibits ZBP1-dependent necroptosis via interaction with host ZBP1. |
WB
Western Blot. Positive WB detected in Recombinant protein. All lanes: E3L antibody at 1:2000. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.| Application Notes | WB:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. |
