WB
Figure. Western Blot; Sample: Recombinant ABCG8, Mouse.IHC
Used in DAB staining on fromalin fixed paraffin- embedded liver tissue.| Product Name | Polyclonal Antibody to ATP Binding Cassette Transporter G8 (ABCG8) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant ABCG8 (Met1~Gln272) expressed in E.coli. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:0.01-2µg/mL IHC:5-20µg/mL |
|
| Species Reactivity | MouseRat |
| Concentration | 0.5mg/ml |
| Purification | Protein A |
| Gene Symbol | ABCG8 |
|---|---|
| Gene Synonyms | GBD4 STSL STSL1 |
| Gene Full Name | ATP binding cassette subfamily G member 8 |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008] |
| Alternative Names | ABC-G8 STSL Gallbladder Disease 4 Sterolin 2 ATP-binding cassette sub-family G member 8 |
| Molecular Weight(MW) | 34kDa |
| Cellular Localization | Cell membrane,Membrane. |
| SwissProt ID | Q9H221 |
|---|
WB
Figure. Western Blot; Sample: Recombinant ABCG8, Mouse.
IHC
Used in DAB staining on fromalin fixed paraffin- embedded liver tissue.| Application Notes | WB:0.01-2µg/mL IHC:5-20µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. |
| Storage Buffer | Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
