WB
Western Blot analysis of 293T COLO cells using CD130 Polyclonal Antibody diluted at 1:500.IHC
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.ICC/IF
Immunofluorescence analysis of NIH/3T3 cells, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.| Product Name | CD130/gp130 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD130/gp130. AA range:748-797. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 ICC/IF:1:200-1:1000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IL6ST |
|---|---|
| Gene Synonyms | CD130 GP130 HIES4 IMD94 STWS2 CDW130 HIES4A HIES4B IL-6RB sGP130 |
| Gene Full Name | interleukin 6 cytokine family signal transducer |
| Gene Summary | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] |
| Alternative Names | IL6ST Interleukin-6 receptor subunit beta IL-6 receptor subunit beta IL-6R subunit beta IL-6R-beta IL-6RB CDw130 Interleukin-6 signal transducer Membrane glycoprotein 130 gp130 Oncostatin-M receptor subunit alpha CD antigen CD130 |
| Molecular Weight(MW) | 160 kDa |
| Cellular Localization | [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted . |
WB
Western Blot analysis of 293T COLO cells using CD130 Polyclonal Antibody diluted at 1:500.
IHC
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.
ICC/IF
Immunofluorescence analysis of NIH/3T3 cells, using CD130/gp130 Antibody. The picture on the right is blocked with the synthesized peptide.| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 ICC/IF:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C). |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
