Purified recombinant fragment of human ZBTB16 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
ICC/IFWB
WB:1:500-1:2000 ICC/IF:1:200 - 1:1000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ZBTB16
Gene Synonyms
PLZF ZNF145
Gene Full Name
zinc finger and BTB domain containing 16
Gene Summary
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Alternative Names
PLZF ZNF145 ZBTB16
Molecular Weight(MW)
74 kDa
Cellular Localization
Nucleus.
Application
WB
Western blot analysis using ZBTB16 mouse mAb against Hela (1) cell lysate.
ICC/IF
Immunofluorescence analysis of Hela cells using ZBTB16 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Application Notes
WB:1:500-1:2000 ICC/IF:1:200 - 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.