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FLAP Rabbit mAb

Catalog Number:OM647013
OM647013
Discount Price
OM647013-100ul
100ul
OM647013-50ul
50ul
OM647013-20ul
20ul
Product Profile
Product Name FLAP Rabbit mAb
Antibody Type Primary Antibodies
Immunogen A synthetic peptide of human FLAP.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:1000-1:5000
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ALOX5AP
Gene Synonyms FLAP
Gene Full Name arachidonate 5-lipoxygenase activating protein
Gene Summary This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Alternative Names ALOX5AP
MK-886-binding protein
Molecular Weight(MW) 18 kDa
Cellular Localization Endoplasmic reticulum,Membrane,Nucleus.
Application

WB

Western blot analysis of extracts from K562 cells using FLAP Rabbit mAb at 1:1000.

WB

Western blot analysis of extracts from THP-1,Pancl cells using FLAP Rabbit mAb at 1:500.
Application Notes WB:1:1000-1:5000
Additional Information
Form Liquid
Storage Instructions Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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