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TDP43 Rabbit mAb

Catalog Number:OM647095
OM647095
Discount Price
OM647095-100ul
100ul
OM647095-50ul
50ul
Product Profile
Product Name TDP43 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TARDBP
Gene Synonyms ALS10
TDP-43
Gene Full Name TAR DNA binding protein
Gene Summary ALS10; TDP-43 Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 45 kDa
Cellular Localization Nucleus.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-TDP43 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Rat brain was stained with anti-TDP43 rabbit antibody.

IHC

Human brain was stained with anti-TDP43 rabbit antibody.

IHC

Mouse brain was stained with anti-TDP43 rabbit antibody.

ICC/IF

Immunofluorescence analysis of HEK293. Picture A:TDP43 antibody (red). Picture B: DAPI (blue). Picture C: Merge of A+B.
Application Notes WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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