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Mouse Monoclonal antibody to NCAM-L1

Catalog Number:OM647103
OM647103
Discount Price
OM647103-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to NCAM-L1
Antibody Type Primary Antibodies
Immunogen raised against fetal brain of human origin.
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications WB
WB:1:100-1:1000
Species Reactivity Human
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol L1CAM
Gene Synonyms S10
HSAS
HYCX
MASA
MIC5
SPG1
CAML1
CD171
HSAS1
N-CAML1
NCAM-L1
N-CAM-L1
Gene Full Name L1 cell adhesion molecule
Gene Summary The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
Molecular Weight(MW) 85/140/180/220 kDa
Cellular Localization Cell membrane,Cell projection,Membrane.
Application

WB

NCAM-L1 antibody: Mouse Monoclonal antibody to NCAM-L1. Analysis of Western blotting of NCAM-L1 expression in whole-cell lysates of HeLa (A), HT-29 (B), and Hep G2 (C).

WB

NCAM-L1 antibody: Mouse Monoclonal antibody to NCAM-L1. Analysis of Western blotting of NCAM-L1 expression in whole-cell lysates of T98G (A), SH-SY5Y (B), and SK-N-SH (C).
Application Notes WB:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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