| Product Name | Anti-pan palmitoylation antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICCIFIHCWB |
| WB:1:500-1:2000 IHC:1:50-1:200 ICC:1:100-1:400 IF:1:50-1:200 |
|
| Species Reactivity | All |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Function | Palmitoylation involves the addition of a 16-carbon fatty acid, palmitic acid, to the cysteine residue of proteins by thioester bond. Protein acyl Transferases (PATs) are enzymes responsible for catalyzing the addition of palmitate to the substrate. The process of N-palmitoylation occurs through a thioester intermediate using the thiol group of the cysteine amino acid, followed by a spontaneous rearrangement forming amide linkage. Palmitoylation is known to facilitate various biological activities like interaction of membrane proteins, mediation of protein trafficking and regulation of protein stability and enzyme activity. |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:50-1:200 ICC:1:100-1:400 IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide. |
