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Cullin 3 Rabbit mAb

Catalog Number:OM647143
OM647143
Discount Price
OM647143-100ul
100ul
OM647143-50ul
50ul
OM647143-20ul
20ul
Product Profile
Product Name Cullin 3 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen A synthetic peptide of human Cullin 3.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:5000-1:50000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CUL3
Gene Synonyms CUL-3
PHA2E
NEDAUS
Gene Full Name cullin 3
Gene Summary This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Alternative Names CUL-3
PHA2E
Molecular Weight(MW) 89 kDa
Cellular Localization Cell projection,Cilium,Cytoplasm,Cytoskeleton,Flagellum,Golgi apparatus,Nucleus.
Application

WB

Western blot analysis of extracts from K562, 3T3, HeLa cells using Cullin 3 Rabbit mAb at 1:1000.

WB

Western blot analysis of extracts from Rat spleen tissue using Cullin 3 Rabbit mAb at 1:1000.
Application Notes WB:1:5000-1:50000
Additional Information
Form Liquid
Storage Instructions Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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