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Artemin Rabbit mAb

Catalog Number:OM647210
OM647210
Discount Price
OM647210-100ul
100ul
OM647210-50ul
50ul
OM647210-20ul
20ul
Product Profile
Product Name Artemin Rabbit mAb
Antibody Type Primary Antibodies
Immunogen A synthetic peptide of human Artemin.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:1000-1:5000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ARTN
Gene Synonyms ART
EVN
NBN
ENOVIN
Gene Full Name artemin
Gene Summary This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016]
Alternative Names ART
EVN
NBN
ENOVIN
Molecular Weight(MW) 23 kDa
Cellular Localization Secreted.
Application

WB

Western blot detection of Artemin in K562,Rat Brain,C6,3T3,Hela cell lysates using Artemin antibody(1:1000 diluted).
Application Notes WB:1:1000-1:5000
Additional Information
Form Liquid
Storage Instructions Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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