IHC
Immunohistochemistry analysis of paraffin embedded Rat lung using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC stainingIHC
Immunohistochemistry analysis of paraffin embedded Human liver using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC stainingIHC
Immunohistochemistry analysis of paraffin embedded Mouse kidney using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC stainingICC/IF
Immunofluorescence analysis of NIH/3T3 cells using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens).Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining| Product Name | ITPR2 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC |
| IHC:1:50 - 1:200 ICC/IF:1:50 - 1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITPR2 |
|---|---|
| Gene Synonyms | ANHD IP3R2 CFAP48 INSP3R2 |
| Gene Full Name | inositol 1,4,5-trisphosphate receptor type 2 |
| Gene Summary | The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015] |
| Alternative Names | ANHD IP3R2 CFAP48 INSP3R2 ITPR2 |
| Molecular Weight(MW) | 308 kDa |
| Cellular Localization | cell cortex, endoplasmic reticulum, nucleoplasm, plasma membrane. |
IHC
Immunohistochemistry analysis of paraffin embedded Rat lung using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining
IHC
Immunohistochemistry analysis of paraffin embedded Human liver using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining
IHC
Immunohistochemistry analysis of paraffin embedded Mouse kidney using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining
ICC/IF
Immunofluorescence analysis of NIH/3T3 cells using ITPR2 Rabbit pAb at dilution of 1:100 (40x lens).Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining| Application Notes | IHC:1:50 - 1:200 ICC/IF:1:50 - 1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
