Synthesized peptide derived from internal of Human CELSR1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IF
ICC/IF:1:100-1:500
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
CELSR1
Gene Synonyms
ME2 YNS FMI2 CDHF9 HFMI2 ADGRC1 LMPHM9
Gene Full Name
cadherin EGF LAG seven-pass G-type receptor 1
Gene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]
Cellular Localization
Cell membrane,Membrane.
Application
ICC/IF
Immunofluorescence analysis of MCF-7 cells, using CELSR1 antibody.
Application Notes
ICC/IF:1:100-1:500
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.