raised against amino acids
268-284 of TLR9 of human origin.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
WB
WB:1:100-1:1000
Species Reactivity
HumanMouseRat
Concentration
0.1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
TLR9
Gene Synonyms
CD289
Gene Full Name
toll like receptor 9
Gene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]