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Rabbit anti-DUX4 Polyclonal antibody

Catalog Number:OM647580
OM647580
Discount Price
OM647580-100ul
100ul
Product Profile
Product Name Rabbit anti-DUX4 Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Human Double homeobox protein 4 protein (217-402AA).
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-1:5000
IHC:1:20-1:200
Species Reactivity Human
Concentration 1mg/ml
Purification Protein G
Target Information
Gene Symbol DUX4
Gene Synonyms DUX4L
Gene Full Name double homeobox 4
Gene Summary This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Alternative Names DUX4 antibody
DUX10Double homeobox protein 4 antibody
Double homeobox protein 10 antibody
Molecular Weight(MW) 45 kDa
Cellular Localization Cytoplasm,Nucleus.
Database Links
SwissProt ID Q9UBX2
Application

WB

Western Blot. All lanes: DUX4 antibody at 1:2000. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.

IHC

Immunohistochemistry of paraffin-embedded human testis tissue using DUX4 Antibody at dilution of 1: 100.
Application Notes WB:1:500-1:5000
IHC:1:20-1:200
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
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