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Tuberin Rabbit mAb

Catalog Number:OM647614
OM647614
Discount Price
OM647614-100ul
100ul
OM647614-50ul
50ul
Product Profile
Product Name Tuberin Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IF-PWB
WB:1:2000-1:10000
IF-P:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TSC2
Gene Synonyms LAM
TSC4
PPP1R160
Gene Full Name TSC complex subunit 2
Gene Summary This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022]
Alternative Names TSC2
TSC4
Tuberin
Tuberous sclerosis 2 protein
Molecular Weight(MW) 201 kDa
Cellular Localization Cytoplasm.
Database Links
SwissProt ID P49815
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the primary antibody was used at 4℃ over night with a 1:5000 dilution . The Dilight 800-conjugated Goat anti-Rabbit antibody was used to detect the antibody.

WB

Various whole cell lysates were separated by 4-8% SDS-PAGE, and the membrane was blotted with anti-Tuberin antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IF-P

Fluorescence immunohistochemical analysis of Human kidney.
Application Notes WB:1:2000-1:10000
IF-P:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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