WB
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.WB
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.| Product Name | GDNF Ab |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human GDNF. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GDNF |
|---|---|
| Gene Synonyms | ATF ATF1 ATF2 HSCR3 HFB1-GDNF |
| Gene Full Name | glial cell derived neurotrophic factor |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
| Alternative Names |
ATF1 ATF2 gdnf HFB1 GDNF hGDNF HSCR3 |
| Molecular Weight(MW) | 24 kDa(Observed band size: 26 kDa) |
| Cellular Localization | Secreted. |
| SwissProt ID | P39905 |
|---|
WB
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
WB
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.| Application Notes | WB:1:1000-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
| Storage Buffer | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
