Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 1 (CXCL1)
Antibody Type
Primary Antibodies
Immunogen
Recombinant CXCL1 (Ala25~Lys96) expressed in E.coli.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB:0.01-2µg/mL
Species Reactivity
MouseRat
Concentration
0.5mg/ml
Purification
Protein A
Target Information
Gene Symbol
CXCL1
Gene Synonyms
FSP GRO1 GROa MGSA NAP-3 SCYB1 MGSA-a
Gene Full Name
C-X-C motif chemokine ligand 1
Gene Summary
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]