Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 1 (CXCL1)
Antibody Type
Primary Antibodies
Immunogen
Recombinant CXCL1 (Ala25~Lys96 (Accession # P14095)) expressed in E.coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
IHCWB
IHC:5-20µg/mL WB:1:200-1:2000
Species Reactivity
Rat
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
CXCL1
Gene Synonyms
FSP GRO1 GROa MGSA NAP-3 SCYB1 MGSA-a
Gene Full Name
C-X-C motif chemokine ligand 1
Gene Summary
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]