The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Alternative Names
FLJ20032 MGC125715 OTTHUMP00000161869 probable methylcytosine dioxygenase TET2 Protein Ayu17 449 ten-eleven translocation 2 ten-eleven translocation 2 protein Tet 2 tet oncogene 2 tet oncogene family member 2