ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-NMDAR2B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GRIN2B |
|---|---|
| Gene Synonyms | DEE27 EIEE27 GluN2B GluRepsilon2 hNR3 MRD6 NMDAR2B NR2B NR3 |
| Gene Full Name | glutamate ionotropic receptor NMDA type subunit 2B |
| Gene Summary | This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017] |
| Alternative Names | GluN2B(alt_5'UTR) glutamate [NMDA] receptor subunit epsilon-2 glutamate receptor glutamate receptor subunit epsilon-2 glutamate receptor ionotropic N-methyl D-aspartate 2B glutamate receptor ionotropic NMDA2B GRIN 2B HGNC:4586 hNR 3 MGC142178 MGC142180 N-methyl D-aspartate receptor subtype 2B N-methyl-D-aspartate receptor subunit 2B N-methyl-D-aspartate receptor subunit 3 NMDAR2B NMDE2 NME2 NR2B |
| Molecular Weight(MW) | 166kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane, Postsynaptic cell membrane, Late endosome, Lysosome, Cytoplasm, cytoskeleton |
| SwissProt ID | Q13224 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
