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Anti-PRAME antibody-HRP

Catalog Number:OM660969-HRP
Human;Mouse;Rat
WB;IHC
OM660969-HRP
Discount Price
OM660969-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-PRAME antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PRAME
Gene Synonyms MAPE
OIP4
CT130
OIP-4
Gene Full Name PRAME nuclear receptor transcriptional regulator
Gene Summary This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Molecular Weight(MW) 58kDa
Source Rabbit
Cellular Localization Nucleus,Cell membrane,Cytoplasm
Database Links
SwissProt ID P78395
Application

WB

Western blot analysis using PRAME antibody against Hela(1),K562(2),Huvec(3),Nih3t3(4),Cos-7(5),C2C12(6),Hek293(7),Mcf-7(8),Jurkat(9) cell .

WB

Western blot analysis using PRAME antibody against Mouse spleen tissue(1) .

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using PRAME antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using PRAME antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using PRAME antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using PRAME antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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