ICC/IF
Immunofluorescence analysis of A549 cells using CD130 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-CD130 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IL6ST |
|---|---|
| Gene Synonyms | 5133400A03Rik CD130 CDW130 D13Ertd699e GP130 HIES4 HIES4A HIES4B IL-6RB IMD94 sGP130 STWS2 |
| Gene Full Name | interleukin 6 cytokine family signal transducer |
| Gene Summary | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] |
| Alternative Names | CD130 antigen gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form gp130 oncostatin M receptor GP130-RAPS IL-6 receptor subunit beta IL-6R subunit beta IL-6R-beta IL-6RB IL6R-beta interleukin receptor beta chain interleukin-6 signal transducer LIF receptor/IL-6 receptor complex component membrane glycoprotein 130 membrane glycoprotein gp130 oncostatin-M receptor subunit alpha soluble receptor |
| Molecular Weight(MW) | 104kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P40189 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using CD130 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
