ICC/IF
Immunofluorescence analysis of Hela cells using PAK3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-PAK3 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | PAK3 |
|---|---|
| Gene Synonyms | 5330420P17Rik A130002K10Rik alpha-PAK ARA beta-PAK bPAK D16Ertd269e gamma-PAK IDDMSSD KNO2 mKIAA4182 MRX30 MRX47 OPHN3 p65-PAK PAK-1 PAK-2 PAK-3 PAK3beta PAK65 Pak65alpha Pak65beta Paka PAKalpha PAKgamma Stk4 XLID30 |
| Gene Full Name | p21 (RAC1) activated kinase 3 |
| Gene Summary | The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2017] |
| Alternative Names | activated protein kinase alpha ADRB2 adriamycin resistance-associated alpha-PAK aPAK beta-PAK BPAK CDC42/RAC effector kinase PAK-A CDC42/RAC effector kinase PAK-B CDKN1A CLAP EC 2.7.11.1 gamma pak gamma-PAK hPAK3 kinase PAK1 oligophrenin-3 p21 (CDKN1A)-activated kinase 1 p21 (CDKN1A)-activated kinase 2 p21 (CDKN1A)-activated kinase 3 P21 CDKN1A-activated kinase 1 p21 protein (Cdc42/Rac)-activated kinase 1 p21 protein (Cdc42/Rac)-activated kinase 2 p21 protein (Cdc42/Rac)-activated kinase 3 p21-activated kinase 1 p21-activated kinase 2 p21-activated kinase 3 p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog yeast) p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related) p21cdc42/rac1-activated serine/threonine kinase p58 p65-PAK p68-PAK PAK 1 PAK alpha PAK beta PAK gamma PAK-1 PAK-2 PAK-3 PAK-a PAK-B PAK-y protein kinase protein kinase MUK2 S6/H4 kinase serine/threonine-protein kinase PAK 2-like STE20 homolog yeast yPAK |
| Molecular Weight(MW) | 62kDa(observed：58kDa) |
| Cellular Localization | Cytoplasm |
| SwissProt ID | O75914 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using PAK3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
