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Anti-TNFRSF18 antibody

Catalog Number:OM661566
OM661566
Discount Price
OM661566-100ul
1~2 Week
100ul
OM661566-50ul
50ul
OM661566-20ul
1~2 Week
20ul
1~2 Week
Product Profile
Product Name Anti-TNFRSF18 antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TNFRSF18
Gene Synonyms AITR
CD357
ENERGEN
GITR
GITR-D
Gene Full Name TNF receptor superfamily member 18
Gene Summary This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
Alternative Names activation-inducible TNFR family receptor
AITR
GITR
TNF receptor homolog
similar to murine glucocorticoid-induced TNFR-related protein
glucocorticoid-induced TNFR-related protein
PRO364
TNF receptor superfamily activation-inducible protein
tumor necrosis factor receptor superfamily
member 18
UNQ319
variant (4) contains an extra coding segment
which leads to a frame shift
compared to variant 1 and 3
resulting protein (isoform 4) contains a transmembrane domain (identical to variant 1 and 3) and a longer cytoplasmic domain with a sequence different
Molecular Weight(MW) 26kDa
Cellular Localization Cell membrane
Database Links
SwissProt ID Q9Y5U5
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
validation
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