This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Alternative Names
brain protein specifically expressed in the developing ventral brainstem and spinal cord recognized by sera of patients with paraneoplastic opsoclonus and breast cancer neuro-oncological ventral antigen 1 onconeural ventral antigen 1 paraneoplastic Ri antigen ventral neuron-specific protein 1