ELISA
Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-NSD1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NSD1 |
|---|---|
| Gene Synonyms | ARA267 KMT3B SOTOS SOTOS1 STO |
| Gene Full Name | nuclear receptor binding SET domain protein 1 |
| Gene Summary | This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Sep 2018] |
| Alternative Names | androgen receptor coactivator 267 kDa protein androgen receptor-associated coregulator 267 androgen receptor-associated protein of 267 kDa ARA267-a H3-K36-HMTase H4-K20-HMTase histone-lysine N-methyltransferase H3 lysine-36 and H4 lysine-20 specific lysine N-methyltransferase 3B NR-binding SET domain-containing protein nuclear receptor SET domain-containing protein 1 nuclear receptor-binding SET domain-containing protein 1 |
| Molecular Weight(MW) | 296kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus;Chromosome |
| SwissProt ID | Q96L73 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
