The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]
Alternative Names
beta-hexosaminidase beta-N-acetylglucosaminidase beta-N-acetylhexosaminidase bifunctional protein NCOAT hyaluronidase in meningioma meningioma expressed antigen 5 (hyaluronidase) meningioma-expressed antigen 5 MGEA5 N-acetyl-beta-D-glucosaminidase N-acetyl-beta-glucosaminidase nuclear cytoplasmic O-GlcNAcase and acetyltransferase protein O-GlcNAcase-like