ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-Complement factor B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description |
|
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CFB |
|---|---|
| Gene Synonyms | AHUS4 ARMD14 BF BFD C2 CFAB CFBD FB FBI12 GBG H2-Bf PBF2 |
| Gene Full Name | complement factor B |
| Gene Summary | This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008] |
| Alternative Names | alternative-complement pathway C3/C5 convertase B-factor properdin C3 proaccelerator C3 proactivator C3/C5 convertase complement component 2 (within H-2S) DADB-122G4.5 Factor B FBI12 glycine-rich beta-glycoprotein histocompatibility 2 complement component factor B MHC factor B MHC factor B precursor peptide properdin properdin B properdin factor B |
| Molecular Weight(MW) | 85kDa |
| Source | Rabbit |
| Cellular Localization | Secreted;Cell surface |
| SwissProt ID | P00751 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
