This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Alternative Names
chondroitin sulfate proteoglycan 2 (versican) chondroitin sulfate proteoglycan core protein chondroitin sulfate proteoglycan core protein 2 chondroitin sulfate proteoglycan core protein PG-M(V3) GHAP glial hyaluronate-binding protein hyaluronan-binding chondroitin sulfate proteoglycan hyaluronan-binding proteoglycan large fibroblast proteoglycan PG-M PG-M core protein PGM V1 Neo versican proteoglycan Versican V0 WGN 1