The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Alternative Names
acetate-CoA ligase acetyl-CoA synthetase acetyl-Coenzyme A synthetase 1 (ADP forming) ACSL1 isoform a ACSL1 isoform c Acyl CoA synthetase long chain acyl-CoA synthetase 1 arachidonate--CoA ligase fatty acid Coenzyme A ligase long chain 2 fatty-acid-Coenzyme A ligase long-chain 1 fatty-acid-Coenzyme A ligase long-chain 2 L LACS2 LACS 1 LACS 2 lignoceroyl-CoA synthase long-chain acyl-CoA synthetase 1 long-chain acyl-CoA synthetase 2 long-chain fatty acid-CoA ligase 2 long-chain fatty-acid-coenzyme A ligase 1 long-chain-fatty-acid--CoA ligase liver isozyme OTTHUMP00000218457 OTTHUMP00000218460 OTTHUMP00000218462 OTTHUMP00000218465 palmitoyl-CoA ligase 1 palmitoyl-CoA ligase 2 paltimoyl-CoA ligase 1 phytanate--CoA ligase