Predicted to enable adenyl-nucleotide exchange factor activity. Involved in chaperone-mediated protein complex assembly and protein import into mitochondrial matrix. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis. [provided by Alliance of Genome Resources, Jun 2026]
Alternative Names
epididymis secretory sperm binding protein Li 5a heat shock 70-related protein APG-2 heat shock 70kD protein 4 Heat shock protein heat shock protein 4 heat shock protein family A member 4 heat shock protein family H member 2 heat shock protein 110 kDa hsp70 RY IRP94 ischemia responsive 94 kDa protein