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Anti-TNF antibody

Catalog Number:OM663404
OM663404
Discount Price
OM663404-100ul
100ul
OM663404-50ul
50ul
OM663404-20ul
20ul
Product Profile
Product Name Anti-TNF antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TNF
Gene Synonyms DIF
IMD127
TNF-a
TNF-alpha
TNFA
TNFalpha
Tnfsf1a
TNFSF2
TNLG1F
Gene Full Name tumor necrosis factor
Gene Summary This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
Alternative Names APC1 protein
cachectin
cell apoptosis-related protein
cytokine
DADB-70P7.1
pro-tumor necrosis factor
TNF alpha
TNF superfamily
TNF superfamily member 2
TNF 伪
TNF
macrophage-derived
TNF
monocyte-derived
TNF-a
TNF伪
tumor necrosis factor
tumor necrosis factor ligand 1F
tumor necrosis factor ligand superfamily member 2
tumor necrosis factor precursor
tumor necrosis factor-alpha
tumor necrotic factor alpha
Molecular Weight(MW) 25kDa
Source Rabbit
Cellular Localization Cell membrane;Membrane;Secreted
Database Links
SwissProt ID P01375
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
validation
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