microtubule associated protein 1 light chain 3 alpha/microtubule associated protein 1 light chain 3 beta
Gene Summary
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]/The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]
Alternative Names
autophagy-related protein LC3 A autophagy-related protein LC3 B autophagy-related ubiquitin-like modifier LC3 A autophagy-related ubiquitin-like modifier LC3 B LC3 LC3-I LC3-II LC3-like protein 1 lc3a lc3b lc3b3 LC3I LC3II MAP1 light chain 3-like protein 1 MAP1 light chain 3-like protein 2 MAP1A/1B MAP1A/1B LC3 MAP1A/1B light chain 3 A MAP1A/1B light chain 3 B MAP1A/MAP1B LC3 A MAP1A/MAP1B LC3 B MAP1A/MAP1B LC3 B-like MAP1A/MAP1B light chain 3 A MAP1A/MAP1B light chain 3 B MAP1A/MAP1B light chain 3 B-like MAP1A1B-LC3 microtubule-associated protein 1-light chain 3A microtubule-associated proteins 1A/1B light chain 3 microtubule-associated proteins 1A/1B light chain 3 beta 2 microtubule-associated proteins 1A/1B light chain 3A microtubule-associated proteins 1A/1B light chain 3B Microtubule-associated proteins 1A/1B light chain 3B-like protein./autophagy-related protein LC3 B autophagy-related ubiquitin-like modifier LC3 B LC3 LC3-II lc3b lc3b3 LC3II MAP1 light chain 3-like protein 2 MAP1A/1B MAP1A/1B LC3 MAP1A/1B light chain 3 B MAP1A/MAP1B LC3 B MAP1A/MAP1B LC3 B-like MAP1A/MAP1B light chain 3 B MAP1A/MAP1B light chain 3 B-like MAP1A1B-LC3 microtubule-associated proteins 1A/1B light chain 3 microtubule-associated proteins 1A/1B light chain 3 beta 2 microtubule-associated proteins 1A/1B light chain 3B Microtubule-associated proteins 1A/1B light chain 3B-like protein