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Anti-PERK antibody

Catalog Number:OM663473
OM663473
Discount Price
OM663473-100ul
100ul
OM663473-50ul
50ul
OM663473-20ul
20ul
Product Profile
Product Name Anti-PERK antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EIF2AK3
Gene Synonyms PEK
PERK
WRS
Gene Full Name eukaryotic translation initiation factor 2 alpha kinase 3
Gene Summary The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Alternative Names 2.7.11.1
eIF-2 alpha kinase
eIF-2 protein kinase
OTTHUMP00000207187
OTTHUMP00000207188
pancreatic eIF-2 alpha kinase
pancreatic eIF-2alpha kinase
pancreatic EIF2-alpha kinase
PKR-like ER kinase
PRKR-like endoplasmic reticulum kinase
protein tyrosine kinase EIF2AK3
Molecular Weight(MW) 125kDa
Source Rabbit
Cellular Localization Endoplasmic reticulum membrane
Database Links
SwissProt ID Q9NZJ5
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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