This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Alternative Names
DKFZp686G01254 krueppel-related zinc finger protein cKrox RP11-307C12.9 T-helper-inducing POZ/Krueppel-like factor unnamed protein product Vzinc finger and BTB domain containing 7B zinc finger and BTB domain containing 15 zinc finger protein 67 zinc finger protein 67 homolog zinc finger protein 857B zinc finger protein Th-POK zinc-finger transcription factor