ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-TAB2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TAB2 |
|---|---|
| Gene Synonyms | 1110030N06Rik A530078N03Rik CHTD2 MAP3K7IP2 mKIAA0733 TAB-2 |
| Gene Full Name | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
| Gene Summary | The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Alternative Names | FLJ21885 MAP3K7IP2 mitogen-activated protein kinase kinase kinase 7-interacting protein 2 OTTHUMP00000017388 TAB2 Tak1 binding protein 2 TAK1-binding protein 2 TGF-beta-activated kinase 1-binding protein 2 |
| Molecular Weight(MW) | 76kDa |
| Source | Rabbit |
| Cellular Localization | Membrane;Endosome membrane;Lysosome membrane;Cytoplasm, cytosol |
| SwissProt ID | Q9NYJ8 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
