This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
Alternative Names
CDK5 activator-binding protein C53 CDK5 regulatory subunit associated protein IC53-2 IC53-2 ischemic heart CDK5 activator-binding protein C53 LXXLL/leucine-zipper-containing ARF-binding protein LXXLL/leucine-zipper-containing ARFbinding protein OK/SW-cl.114
Molecular Weight(MW)
56kDa
Source
Rabbit
Cellular Localization
Endoplasmic reticulum membrane;Cytoplasm;Nucleus;Cytoplasm, cytoskeleton, microtubule organizing center, centrosome;Cytoplasm, cytoskeleton