| Product Name | Anti-IL2RA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IL2RA |
|---|---|
| Gene Synonyms | CD25 IDDM10 IL2R IMD41 p55 TCGFR |
| Gene Full Name | interleukin 2 receptor subunit alpha |
| Gene Summary | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| Alternative Names | IL 2 RA IL 2 receptor IL 2R IL 2R subunit alpha il-2 receptor alpha IL-2 receptor subunit alpha IL-2R subunit alpha IL2 RA IL2 RA antibody IL2 receptor IL2 receptor subunit alpha IL2R subunit alpha Il2ra antibody interleukin 2 receptor alpha interleukin-2 receptor alpha interleukin-2 receptor precursor Interleukin2 receptor subunit alpha sIL 2R soluble IL 2 receptor TAC antigen |
| Molecular Weight(MW) | 30kDa |
| Source | Rabbit |
| Cellular Localization | Membrane |
| SwissProt ID | P01589 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
