Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.
Conjugation
Alexa Fluor® 488
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
ELISAFCWB
WB:1:500-1:2000 FC:1:200-1:400 ELISA:1:10000
Species Reactivity
Human
Concentration
1μg/μl
Purification
Affinity purified
Target Information
Gene Symbol
GRIA2
Gene Synonyms
GluA2 GluR2 gluR-B GluR-K2
Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.
Molecular Weight(MW)
98.8kDa
Application
WB
Western blot analysis using GRIA2 mouse
mAb against HeLa (1) cell lysate.
FC
Flow cytometric analysis of SK-N-SH cells
using GRIA2 mouse mAb (green) and
negative control (red)
Application Notes
WB:1:500-1:2000 FC:1:200-1:400 ELISA:1:10000
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer
Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.