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GRIA2 Mouse Monoclonal Antibody Alexa Fluor® 488 Conjugate

Catalog Number:OM670623
OM670623
Discount Price
OM670623-100ul
100ul
Product Profile
Product Name GRIA2 Mouse Monoclonal Antibody Alexa Fluor® 488 Conjugate
Antibody Type Primary Antibodies
Immunogen Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.
Conjugation Alexa Fluor® 488
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications ELISAFCWB
WB:1:500-1:2000
FC:1:200-1:400
ELISA:1:10000
Species Reactivity Human
Concentration 1μg/μl
Purification Affinity purified
Target Information
Gene Symbol GRIA2
Gene Synonyms GluA2
GluR2
gluR-B
GluR-K2
Gene Summary Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.
Molecular Weight(MW) 98.8kDa
Application

WB

Western blot analysis using GRIA2 mouse mAb against HeLa (1) cell lysate.

FC

Flow cytometric analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and negative control (red)
Application Notes WB:1:500-1:2000
FC:1:200-1:400
ELISA:1:10000
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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