| Product Name | ANGPTL4 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human ANGPTL4. AA range:301-350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ANGPTL4 |
|---|---|
| Gene Synonyms | NL2 ARP4 FIAF HARP PGAR HFARP TGQTL UNQ171 pp1158 |
| Gene Full Name | angiopoietin like 4 |
| Gene Summary | This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013] |
| Alternative Names | ANGPTL4 ARP4 HFARP PGAR PP1158 PSEC0166 Angiopoietin-related protein 4 Angiopoietin-like protein 4 Hepatic fibrinogen/angiopoietin-related protein HFARP |
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Secreted . Secreted , extracellular space , extracellular matrix . The unprocessed form interacts with the extracellular matrix (PubMed:17068295 , PubMed:21398697) . This may constitute a dynamic reservoir , a regulatory mechanism of the bioavailability of ANGPTL4 (Probable) . . |
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA. |
