IHC
Immunohistochemistry of paraffin-embedded human melanoma using CDS1 Antibody at dilution of 1:100ICC/IF
Immunofluorescent analysis of Hela cells using CDS1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)| Product Name | CDS1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Phosphatidate cytidylyltransferase 1 protein (6-85AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC |
| IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | CDS1 |
|---|---|
| Gene Synonyms | CDS 1 |
| Gene Full Name | CDP-diacylglycerol synthase 1 |
| Gene Summary | Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008] |
| Alternative Names | CDS1 CDS Phosphatidate cytidylyltransferase 1 CDP-DAG synthase 1 CDP-DG synthase 1 CDP-diacylglycerol synthase 1 CDS 1 CDP-diglyceride pyrophosphorylase 1 CDP-diglyceride synthase 1 CTP:phosphatidate cytidylyltransferase 1 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
IHC
Immunohistochemistry of paraffin-embedded human melanoma using CDS1 Antibody at dilution of 1:100
ICC/IF
Immunofluorescent analysis of Hela cells using CDS1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)| Application Notes | IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Preservative: 0.03% Proclin 300,Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
