WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PLAUR antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: Mouse lung Lane 2: Mouse spleen Predicted band size: 37kDa Observed band size: 62kDa| Product Name | PLAUR Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:500-1:2000 IF:1:200-1:1000 ELISA:1:5000-1:20000 IP:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PLAUR |
|---|---|
| Gene Synonyms | CD87 UPAR URKR U-PAR |
| Gene Full Name | plasminogen activator, urokinase receptor |
| Gene Summary | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
| Alternative Names | PLAUR MO3 UPAR Urokinase plasminogen activator surface receptor U-PAR uPAR Monocyte activation antigen Mo3 CD antigen CD87 |
| Molecular Weight(MW) | 37kD(Observed band size:34kD) |
| Cellular Localization | Cell junction,Cell membrane,Cell projection,Membrane,Secreted |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PLAUR antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: Mouse lung Lane 2: Mouse spleen Predicted band size: 37kDa Observed band size: 62kDa| Application Notes | WB:1:500-1:2000 IF:1:200-1:1000 ELISA:1:5000-1:20000 IP:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year (Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
