WB
Western Blot Positive WB detected in: Mouse heart tissue, Mouse brain tissue, Mouse liver tissue All lanes: SEPP1 antibody at 1：2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 43 kDa Observed band size: 43, 40 kDaIHC
Immunohistochemistry of paraffin-embedded human kidney tissue using at dilution of 1:100| Product Name | SELENOP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Centromere protein J protein (1082-1248AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| WB:1:500-1:2000 IHC:1:20-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | SELENOP |
|---|---|
| Gene Synonyms | SeP SELP SEPP SEPP1 |
| Gene Full Name | selenoprotein P |
| Gene Summary | This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. The use of alternative polyadenylation sites, one located in between the two SECIS elements, results in two populations of mRNAs containing either both (predominant) or just the upstream SECIS element (PMID:27881738). Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Oct 2018] |
| Alternative Names | Selenoprotein P antibody Selenoprotein P plasma 1 antibody Selp antibody SeP antibody Sepp1 antibody SEPP1_HUMAN antibody |
| Molecular Weight(MW) | 43 kDa |
| Cellular Localization | Secreted |
WB
Western Blot Positive WB detected in: Mouse heart tissue, Mouse brain tissue, Mouse liver tissue All lanes: SEPP1 antibody at 1：2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 43 kDa Observed band size: 43, 40 kDa
IHC
Immunohistochemistry of paraffin-embedded human kidney tissue using at dilution of 1:100| Application Notes | WB:1:500-1:2000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
